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ANTINUCLEAR ANTIBODIES HEp-2 (ANA-HEp-2)
44508
IFA – Complete kit, 10 slides x 6 wells
44509
IFA – Complete kit, 10 slides x 12 wells
44546
IFA – Slide Box, 10 slide x 6 wells
44547
IFA – Slide Box, 10 slide x 12 wells
AUTOANTIBODIES DUO
44874
IFA – Slide Box, 10 slide x 6 wells / HEp2/ML.
ANA – SCREENING
44785
ELISA kit, 96 test
Purified SSA(Ro), SSB(La), Sm/RNP, RNP (70, A
and C), Sm, Scl70, Jo1, dsDNA, ssDNA, nucleosomes,
total histones, PMScl 100, Centromere B
EXTRACTABLE NUCLEAR ANTIGENS ELISA 96 Test
44740
ENA 6-SCREENING
Highly purified SSA (Ro), SSB (La), Sm, Sm/RNP,
Jo1, Scl70
44910
ENA 6-PROFILE
Highly purified SSA (Ro), SSB (La), Sm, Sm/RNP,
Jo1, Scl70
44775
ENA 4-PROFILE
Highly purified SSA, SSB, Sm, Sm/RNP
44755
ANTI-Sm ANTIBODIES
Highly purified human antigen
44770
ANTI Sm/RNP ANTIBODIES
Highly purified human antigen
44765
ANTI SSA (Ro) ANTIBODIES
Highly purified antigen
44750
ANTI SSB (La) ANTIBODIES
Highly purified antigen
44865
ANTI-CENTROMERE B ANTIBODIES (CENP-B)
Recombinant antigen
44864
ANTI-Jo1 ANTIBODIES
Highly purified antigen
44863
ANTI-Scl70 ANTIBODIES
Highly purified antigen
ANTI-RIBOSOMAL P ANTIBODIES (Rib P)
44866
ELISA kit 96 Test.
Highly purified antigen
ANTI-HISTONES ANTIBODIES (HIST)
44862
ELISA kit 96 Test.
Highly purified antigen
ANTI-NUCLEOSOME ANTIBODIES (NUCL)
44861
ELISA kit 96 Test.
Purified antigen
NUCLEOSOME
Anti-nucleosome antibodies are recognized to be especially prevalent in
SLE and drug-induced lupus, since they are detected in 84 - 88 % of
patients. A percentage of 16 - 30 % of patients with lupus have been
reported to have anti-nucleosome antibodies without anti-dsDNA and
anti-histone antibodies.
nDNA / dsDNA
The
Crithidia luciliae
immunofluorescence test for anti-nDNA
antibodies has a high diagnostic specificity, but a fairly high diagnostic
sensitivity for SLE. They are the most frequently detected autoantibodies
associated to SLE: 95% in SLE patients with renal involvement, 50 –
70% in SLE patients without renal involvement and 40% in patients with
inactive SLE. Anti-nDNA antibodies are rarely found in healthy individuals.
Enzyme immunoassay for anti-dsDNA antibodies shows a specificity of
98-100 % for SLE and a sensitivity of 40-60 %. These antibodies are
specially relevant in the course of the disease and they are believed to be
involved in associated kidney diseases.
ANTI-nDNA ANTIBODIES (nDNA)
44818
IFA – Complete kit, 10 slides x 6 wells
44817
IFA – Complete kit, 10 slides x 12 wells
44820
IFA – Slide Box, 10 slides x 6 wells
44819
IFA – Slide Box, 10 slides x 12 wells
Crithidia luciliae
ANTI-dsDNA ANTIBODIES
44705
ELISA kit 96 Test.
Calf thymus antigen
FILAGGRIN
The presence of high levels of antikeratin antibodies (AKA) is strongly
indicative of rheumatoid arthritis. The diagnostic sensitivity for this
disease varies from 30 to 87%, and the diagnostic specificity from 90 to
99%, depending on the study design and the method used. AKA are also
found in one third of rheumatoid arthritis patients with rheumatoid factor
negative. Filaggrin present in the rat esophagus middle third, recognized
by antibodies anti-keratin antibodies (AKA), is extremely sensitive to
temperature changes and may lose its antigenicity when the slides are
not properly refrigerated (2-8ºC) during shipment or storage. Recently
developed methods based on ELISA using citrullinated proteins have
shown to be a more sensitive and specific marker for rheumatoid arthritis,
with a high value as predictors of disease persistance and radiographic
joint damage in early arthritis.
ANTI-KERATIN ANTIBODIES (AKA)
44618
IFA – Complete kit, 48 tests
Controls not included
44517
IFA – Slide Box, 12 slides x 4 wells
Rat Esophagus.
ANTI-CITRULLINATED PROTEIN ANTIBODIES (ACPA)
44860
ELISA kit 96 Tests
Highly purified antigen
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